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Rev. AMRIGS ; 58(1): 61-64, jan.-mar. 2014. ilus
Article in Portuguese | LILACS | ID: biblio-878966

ABSTRACT

A doença de Castleman (DC) é uma rara e benigna desordem linfoproliferativa descrita por Castleman como "hiperplasia hialinizante linfoide". Sua etiologia e patogênese é desconhecida, porém parece haver hiperestimulação antigênica induzida por vírus de forma crônica e mediada por interleucina 6, com alguns casos ligados ao herpes vírus 8 e vírus da imunodeficiência humana (AU)


Castleman's disease (CD) is a rare and benign lymphoproliferative disorder described by Castleman as "hyelinizing lymphoid hyperplasia". Its etiology and pathogenesis are unknown, but there appears to be antigen hyperstimulation chronically induced by virus and mediated by interleukin 6, with some cases related to herpes virus 8 and human immunodeficiency virus (AU)


Subject(s)
Humans , Female , Child , Adolescent , Middle Aged , Castleman Disease/diagnosis , Castleman Disease/classification , Castleman Disease/pathology , Castleman Disease/therapy
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